СТРОМАН Дэвид У. (US),ЧОВХАН Масуд А. (US),АППЕЛЛ Кеннет К. (US)
申请号：
RU2012103458/15
公开号：
RU2012103458A
申请日:
2010.07.02
申请国别(地区):
RU
年份:
2013
代理人:
摘要：
1. A pharmaceutically acceptable composition for topical use of finfloxacin, wherein said composition is suitable for the treatment of ophthalmic, ear and nasal infections. The composition according to claim 1, comprising finfloxacin or a pharmaceutically acceptable salt thereof in a concentration of 0.1-1.0% w / v. 3. The composition according to claim 1, including finfloxacin or its pharmaceutically acceptable salt in a concentration of 0.1-0.5 wt./vol.%. 4. The composition according to claim 1, comprising finfloxacin or a pharmaceutically acceptable salt thereof in a concentration of 0.3-0.4 wt./vol.%. 5. The composition according to claim 1, wherein said composition has a pH of 5.0-7.5.6. The composition according to claim 1, wherein said composition has a pH of 5.0-6.0.7. The composition of claim 1, further comprising an anti-inflammatory agent. A method for treating an ophthalmic, ear or nasal infection, comprising: treating an infection with a pharmaceutically effective amount of a composition comprising finafloxacin. 9. The method of claim 8, wherein said infection is a nasal infection. The method of claim 8, wherein said infection is acute otitis externa or acute otitis media with tympanostomy tubes. The method of claim 8, wherein said composition comprises finfloxacin or a pharmaceutically acceptable salt thereof in a concentration of 0.1-1.0% w / v. 12. The method of claim 8, wherein said composition comprises finfloxacin or a pharmaceutically acceptable salt thereof in a concentration of 0.1-0.5% w / v. 13. The method of claim 8, wherein said composition comprises finfloxacin or a pharmaceutically acceptable salt thereof at a concentration of 0.3-0.4% w / v. The method of claim 8, wherein said composition has a pH of 5.0-7.5.15. The method of claim 8, wherein said composition has a pH of 5.0-6.0.16. The method of claim 8, where the specified1. Фармацевтически приемлемая композиция для местного применения финафлоксацина, причем указанная композиция подход
