Ethyl 2-oxocyclohex-3-enecarboxylate derivatives, preparation method thereof and pharmaceutical composition for use in preventing or treating neurodegenerative disease containing the same
The invention relates to ethoxycyclohexane trio silver ore carboxyelectric conductor, heterogeneous manufacturing method and composition including medicine for prevention or treatment of degenerative brain disease. The chemical formula marked by the invention is a compound with excellent resistance to acetylcholine activity, Acetylcholinesterase inhibitors and therapeutic agents for degenerative brain diseases.본 발명은 에틸 2-옥소사이클로헥스-3-엔카르복실레이트 유도체, 이의 제조방법 및 이를 포함하는 퇴행성 뇌질환 예방 또는 치료용 약학적 조성물에 관한 것으로, 본 발명에 따른 화학식 1로 표시되는 화합물은 아세틸콜린에스테라제 활성 저해 효과가 우수하므로, 아세틸콜린에스테라제 저해제 및 퇴행성 뇌질환 치료제로 유용할 수 있다.
