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MATERIALS AND METHODS RELATING TO MODIFYING THE BINDING OF ANTIBODIES
专利权人:
发明人:
申请号:
EP08806434.0
公开号:
EP2201038B1
申请日:
2008.09.26
申请国别(地区):
EP
年份:
2017
代理人:
摘要:
The present invention relates to antibodies that are obtained by inserting an amino acid sequence capable of binding to a target into the complementarity determining region (CDR) of a parent antibody. The antibody thus obtained has a new binding specificity. For example, the antibodies of the present invention are able to bind to the target, such as &alphav&bgr6 integrin, while retaining one or more of the useful properties of the parent antibody.
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