Jianming Bao,Ping Lan,Huagang Lu,Gergely M. Makara,F. Anthony Romero,Iyassu Sebhat,Dariusz Wodka,Qun Dang,De Michael Chung,Tony S. Gibson,Hongjian Jiang,Daniel K. Cashion
申请号:
US13125345
公开号:
US08329914B2
申请日:
2009.10.22
申请国别(地区):
US
年份:
2012
代理人:
摘要:
Novel compounds of the structural formula (I) are activators of AMP-protein kinase and are useful in the treatment, prevention and suppression of diseases mediated by the AMPK-activated protein kinase. The compounds of the present invention are useful in the treatment of Type 2 diabetes, hyperglycemia, metabolic syndrome, obesity, hypercholesterolemia, and hypertension.