Qun Dang,Tony S. Gibson,Hongjian Jiang,De Michael Chung,Jianming Bao,Jinlong Jiang,Andy Kassick,Ahmet Kekec,Ping Lan,Huagang Lu,Gergely M. Makara,F. Anthony Romero,Iyassu Sebhat,David Wilson,Dariusz W
申请号:
US13124898
公开号:
US08410284B2
申请日:
2009.10.12
申请国别(地区):
US
年份:
2013
代理人:
摘要:
Novel compounds of the structural formula (I) are activators of AMP-protein kinase and are useful in the treatment, prevention and suppression of diseases mediated by the AMPK-activated protein kinase. The compounds of the present invention are useful in the treatment of Type 2 diabetes, hyperglycemia, Metabolic Syndrome, obesity, hypercholesterolemia, and hypertension.