TRAN, THUY-ANH,BLACKBURN, ANTHONY C.,KRAMER, BRYAN A.,NAGURA, MAIKO,SAGE, CARLETON R.,SHIN, YOUNG-JUN,ZOU, NING
申请号：
SG11201401743R
公开号：
SG11201401743RA
申请日:
2012.11.07
申请国别(地区):
SG
年份:
2014
代理人:
摘要：
The present invention relates to compounds of Formula (I) and pharmaceutically acceptable salts, solvates, and hydrates thereof: that are useful in methods of treatment and alleviation of diseases and disorders of the heart, brain, kidney, immune, and reproductive system resulting from ischemia, or reperfusion subsequent to ischemia, and any downstream complication(s) related thereto. The present invention further relates to methods of treatment and alleviation of diseases and disorders of the vasculature resulting from vasoconstriction or hypertension and any downstream complication(s) resulting from elevated blood pressure and/or reduced tissue perfusion.
