Disclosed are a core-shell nanofiber membrane featuring anti-adhesion and preparation method thereof comprising the following steps: solution preparation steps: first, prepare a shell solution by first placing dimethyl formamide and methylene dichloride solution into the sample bottle, and dissolving polycaprolactone in the dimethyl formamide and methylene dichloride solution, preserving the solution in the greenhouse after the solute is completely dissolved prepare a core solution by placing the hyaluronic acid into another sample bottle, wherein the concentration of hyaluronic acid is 1.75 wt% and the electrospinning preparation step: subjecting the prepared solution in the sample bottle to the electrospinning device to form a nanofiber membrane with the core-shell structure, such that the double effects of preventing the tendon adhesion and inhibiting bacterial growth are achieved.一種具有抗沾黏的核、殼奈米纖維薄膜及其製造方法,其步驟包括:溶液製備步驟:首先配置殼的溶液,先將二甲基甲醯胺及二氯甲烷溶液放置樣本瓶內,取聚己內酯溶解於二甲基甲醯胺及二氯甲烷溶液中,待溶質完全溶解後保存於溫室中;配置核的溶液,取玻尿酸放置於另一樣本瓶中,其中玻尿酸濃度為1.75wt%;及電紡製程步驟:將上述已配製好的樣本瓶內之溶液經由電紡裝置形成具有核殼構造的奈米纖維薄膜,以達防止肌腱沾黏及抑菌的雙重功效。10‧‧‧奈米纖維薄膜20‧‧‧內核30‧‧‧外殼
