Manufacture of peanut formulations for oral desensitization

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专利权人:

Inc.;Aimmune Therapeutics

发明人:

Walser, Bryan,Raff, Howard V.

申请号：

AU2016231523

公开号：

AU2016231523B2

申请日:

2016.09.21

申请国别(地区):

AU

年份:

2018

代理人:

摘要：

#$%^&*AU2016231523B220180531.pdf#####ABSTRACT The present application relates to a method for managing the development and manufacturing process of a therapeutically effective formulation. Peanut proteins are characterized from peanut flour and encapsulated formulations made using the peanut flour for oral immunotherapy of peanut allergies. 3907955 1.docx27/9 FIGURE 7 Peanut Flour Diluent Low Dose Strengths (1) First Blend (10 min) Addition of 45% of IV Diluent (2) Second Blend (10 min) I Addition of I___ Remaining Diluent (3) Third Blend (15 min) Addition of Glidant (4) Final Blend and/or Lubricant (5 min) i >；4 (5) Blended Sampling ) Discharge Blended Powder For Encapsulation 4 E (6) Encapsulate in Size 3 HPMC Capsules

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