This pyridone compound or a pharmaceutically acceptable salt thereof is useful, for example, as a prophylactic and/or therapeutic agent for skin diseases and the like. The present invention provides a pyridone compound represented by general formula (I) or a pharmaceutically acceptable salt thereof or the like, which is useful as a prophylactic and/or therapeutic agent for skin diseases. (In the formula, R1 represents an optionally substituted cycloalkyl group or the like; R2 represents a hydrogen atom or the like; R3 represents a hydroxy group or the like; and R4A represents formula (R4A-1) (wherein R4 and R5 may be the same or different and each represents a hydrogen atom or the like) or the like).本發明之吡啶酮化合物或其藥學上容許之鹽例如可用作皮膚疾病等之預防及/或治療劑等。藉由本發明,可提供一種可用作皮膚疾病之預防及/或治療劑之下述通式(I)所表示之吡啶酮化合物或其藥學上容許之鹽等,[式中,R1表示亦可具有取代基之環烷基等,R2表示氫原子等,R3表示羥基等,R4A表示下述式(R4A-1)等]。