This pyridone compound or a pharmaceutically acceptable salt thereof is useful, for example, as a prophylactic and/or therapeutic agent for skin diseases and the like. The present invention provides a pyridone compound represented by general formula (I) or a pharmaceutically acceptable salt thereof or the like, which is useful as a prophylactic and/or therapeutic agent for skin diseases. (In the formula, R1 represents an optionally substituted cycloalkyl group or the like R2 represents a hydrogen atom or the like R3 represents a hydroxy group or the like and R4A represents formula (R4A-1) (wherein R4 and R5 may be the same or different and each represents a hydrogen atom or the like) or the like.)