Ectoparasite treatment devices utilizing heated air and related treatment methods. In some embodiments, the device may comprise a heating assembly positioned within a housing that is configured to generate heated air and a blower, such as a fan, for moving the heated air. The device may further comprise an air diffuser configured to receive heated air from the blower and to mix the heated air to increase uniformity of temperature of the heated air. A tip comprising a plurality of tines with ports may be removably coupled with the housing. The tip may be fluidly coupled with the diffuser. A temperature sensor and temperature control electronics may be configured to use temperature data and adjust the heating assembly such that the heated air delivered through the tip is maintained between a minimum temperature of about 54 degrees Celsius and a maximum temperature of about 62 degrees Celsius.
