PROCESSES OF SYNTHESIZING DIHYDROPYRIDOPHTHALAZINONE DERIVATIVES

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专利权人:

BIOMARIN PHARMACEUTICAL INC

发明人:

WANG BING,CHU DANIEL,LIU YONGBO,JIANG QUAN,LU LEI

申请号：

ZA201205538

公开号：

ZA201205538B

申请日:

2012.07.23

申请国别(地区):

ZA

年份:

2013

代理人:

摘要：

Provided herein are processes for synthesizing dihydropyridophthalazinone derivatives, such as for example, 5-fluoro-8-(4-fluorophenyl)-9-(1-methyl-1H-1,2,4-triazol-5-yl)-8,9-dihydro-2H-pyrido[4,3,2-de]phthalazin-3(7H)-one and its stereoisomers, which are potent poly(ADP-ribose)polymerase (PARP) inhibitors as well as novel synthetic intermediate compounds.

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中国工程科技知识中心

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http://www.ckcest.cn/home/