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用於血液替代品和其他治療用途的優化的氟碳乳劑
专利权人:
ALLIANCE PHAMACEUTICAL CORP.
发明人:
JEFFREY WEERS,DAVID KLEIN,CINDY JOHNSON
申请号:
HK09111280.7
公开号:
HK1133185B
申请日:
2009.12.02
申请国别(地区):
HK
年份:
2013
代理人:
摘要:
The present invention is directed to a stable fluorocarbon emulsion having a continuous aqueous phase and discontinuous fluorocarbon phase comprising two fluorocarbons and surprisingly demonstrates that perfluorodecyl bromide is as effective in stabilizing perfluorooctyl bromide emulsions of certain concentrations than much more highly concentrated perfluorooctyl bromide/perfluorodecyl bromide emulsions without the significant problems experienced in higher concentrated emulsions such as longer organ retention times, formation of PFDB crystals, larger emulsion particles, manufacturing problems and inability of repeat dosing inherent with higher concentrations of perfluorodecyl bromide.
来源网站:
中国工程科技知识中心
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http://www.ckcest.cn/home/

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