Use of PTEN long leader sequences for transmembrane delivery of molecules

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专利权人:

ザ・トラスティーズ・オブ・コランビア・ユニバーシティー・イン・ザ・シティー・オブ・ニューヨーク

发明人:

パーソンズ、ラモン

申请号：

JP2012554034

公开号：

JP6009360B2

申请日:

2011.02.17

申请国别(地区):

JP

年份:

2016

代理人:

摘要：

A composition for delivering cargo molecules across biological membranes is provided comprising (i) a peptide comprising consecutive amino acid residues having the sequence set forth in SEQ ID NO 1 for the transport of a cargo molecule across a biological membrane and (ii) the cargo molecule, wherein the cargo molecule is not a peptide comprising amino acid residues having the sequence set forth in SEQ ID NO 4. Methods of delivering cargo molecules across biological membranes are also provided. Methods of treating a tumor, cancer, a metabolic disorder, and a cardiovascular disorder are also provided.

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中国工程科技知识中心

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