As for this invention, the chemical compound formula (i) or the salt which that pharmacy it can allow (in formula, X - X, as for R - R, A, B, D, and m defined in this bill, as, is,) it regards. In addition as for this invention, the medicine constituent which includes these chemical compounds, it regards the useful intermediate field in the various diseases and usage of these chemical compounds in dealing with the fault, preparation manner, and these manners of these chemical compounds.本発明は、式(I)の化合物又はその薬学的に許容しうる塩(式中、X1~X4、R1~R4、A、B、D、及びmは本明細書に定義されたとおりである)に関する。本発明はまた、これらの化合物を含む医薬組成物、種々の疾患及び障害の処置におけるこれらの化合物の使用方法、これらの化合物の調製方法、ならびにこれらの方法に有用な中間体に関する。