Formula (i) [in formula, m, n, X and X, Y, Y, R and R are, as defined with this bill,] with the chemical compound which is shown. In addition the medicine constituent, it offers also the usage and production manner of the said chemical compound.式(I)[式中、m、n、X1、X2、Y1、Y2、R1及びR2は、本明細書で定義されたとおりである]で示される化合物。また医薬組成物、該化合物の使用方法及び製造方法も提供する。