University of Florida Research Foundation Incorporated
发明人:
Maria Zajac-Kaye,Rony A. Francois
申请号：
US15737545
公开号：
US20180177776A1
申请日:
2016.06.16
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The invention pertains to compositions comprising inhibitors of PI3K, AKT and/or mTOR, one or more 4-quinolinemethanols and a pharmaceutically acceptable excipient. These compositions can contain subtherapeutic amounts of each active ingredient (PI3K, AKT, mTOR, one or more 4-quinolinemethanols and various combinations thereof). The invention also provides a method of treating various forms of cancer, such as breast cancer, prostate cancer, multiple myeloma, hepatocyte carcinoma, brain cancer, lung cancer, non-small cell lung carcinoma, colorectal cancer, melanoma and/or pancreatic cancer.
