2-((2S,3S,4R,5R)-5-((S)-3-AMINO-2-HYDROXYPROP-1-YL)-4-METHOXY-3-(PHENYLSULFONYLMETHYL)TETRAHYDROFURAN-2-YL)ACETALDEHYDE DERIVATIVES AND PROCESS FOR THEIR PREPARATION

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专利权人:

发明人:

Fabio E.S. Souza,Alena Rudolph,Ming Pan,Boris Gorin,Dino Alberico

申请号：

US14369442

公开号：

US20150011776A1

申请日:

2012.12.24

申请国别(地区):

US

年份:

2015

代理人:

摘要：

Disclosed is a compound of formula 1, as shown below, where R1, R2, R3, R4, R5, R6 and R7 are as described herein. Also, disclosed is a process for the preparation of compounds of formula 1, and intermediates used therein. The compound of formula 1 can be useful for preparation of halichondrin analogs such as Eribulin.

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