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PROCEDE DE PRODUCTION DE FORMULATIONS INJECTABLES DE PRODUITS PROTEIQUES HEMODERIVES ET PRODUITS OBTENUS SUIVANT CE PROCEDE
专利权人:
UNIVERSIDAD DE COSTA RICA
发明人:
SEGURA RUIZ, ALVARO,VARGAS ARROYO, MARIANGELA,LEON MONTERO, GUILLERMO,VILLALTA ARRIETA, MAUREN,HERRERA VEGA, MARIA,ANGULO UGALDE, YAMILETH
申请号:
CA2832665
公开号:
CA2832665C
申请日:
2011.04.08
申请国别(地区):
CA
年份:
2020
代理人:
摘要:
The invention relates to a method for producing injectable pharmaceuticalformulations ofblood-derived protein materials, including the steps of fractioning the sourcematerial in apolymer/salt aqueous two-phase system in the presence of phenol, purifying thetopphase of the system by means of precipitation with caprylic acid and purifyingthe bottomphase by means of thermocoagulation, increasing the purity of the materials inbothphases through chromatography, removing viral particles by means of thenanofiltration ofboth preparations, and formulating, stabilizing, and packaging the resultingmaterials.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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