Michael F. CONCINO,Bettina STRACK-LOGUE,Muthuraman MEIYAPPAN,Angela W. NORTON,Bohong ZHANG,Andrea ISKENDERIAN,Lieh Yoon LOW,Dianna LUNDBERG,Alla ROMASHKO,Hicham NAIMY
申请号：
US15503223
公开号：
US20170232076A1
申请日:
2015.08.11
申请国别(地区):
US
年份:
2017
代理人:
摘要：
A targeted therapeutic including a lysosomal enzyme and a lysosomal targeting moiety that is a peptide containing at least one N-linked glycosylation site. Methods of producing the targeted therapeutic may include nucleotide acids encoding the same and host cells co-expressing GNPT. Pharmaceutical compositions comprising the targeted therapeutic and methods of using the same to treat a lysosomal storage disease.
