DIJKSTRA, ZWAANTJE JOHANNA,JEURISSEN, FRANCISCUS JOHANNES HUBERTUS,VAN GENUCHTEN, MARTINA HENRICA MARIA,HUISMAN, JACOB
申请号：
CA3073332
公开号：
CA3073332A1
申请日:
2018.09.28
申请国别(地区):
CA
年份:
2019
代理人:
摘要：
The invention relates to a process for the purification of a neutral human milk oligosaccharide (HMO) from a fermentation broth, the process comprising the steps of: (i) separating biomass from the fermentation broth to provide a crude solution； (ii) treating the crude solution with: (a) a cation- exchange material； (b) an anion-exchange material； and (c) a cation-exchange adsorbent resin； thereby obtaining a purified solution containing the neutral human milk oligosaccharide. Further, the invention relates to a process for fermentatively producing HMO in a fermentation broth and purifying the HMO from the broth.
