The Board of Trustees of the Leland Stanford Junior University
发明人:
Gabriel Nestor Sanchez,Scott L. Delp,Mark J. Schnitzer,Michael E. Llewellyn
申请号：
US14546085
公开号：
US10499797B2
申请日:
2014.11.18
申请国别(地区):
US
年份:
2019
代理人:
摘要：
Biological tissue such as skeletal and cardiac muscle can be imaged by using an objective-based probe in the tissue and scanning at a sufficiently fast rate to mitigate motion artifacts due to physiological motion. According to one example embodiment, such a probe is part of a system that is capable of reverse-direction high-resolution imaging without needing to stain or otherwise introduce a foreign element used to generate or otherwise increase the sensed light. The probe can include a light generator for generating light pulses that are directed towards structures located within the thick tissue. The system can additionally include aspects that lessen adverse image-quality degradation. Further, the system can additionally be constructed as a hand-held device.
