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Method for automated, large-scale measurement of the molecular flux rates of the proteome or the organeome using mass spectrometry
专利权人:
Marc K. Hellerstein
发明人:
Marc K. Hellerstein
申请号:
US13410183
公开号:
US08481478B2
申请日:
2012.03.01
申请国别(地区):
US
年份:
2013
代理人:
摘要:
Disclosed here is a method for measuring the kinetics (i.e., the molecular flux rates—synthesis and breakdown or removal rates) of a plurality of proteins or organic metabolites in living systems. The methods may be accomplished in a high-throughput, large-scale automated manner, by using existing mass spectrometric profiling techniques and art well known in the fields of static proteomics and static organeomics, without the need for additional biochemical preparative steps or analytic/instrumental devices.
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中国工程科技知识中心
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