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AGENT DE CICATRISATION DE PLAIE
专利权人:
Sanyo Chemical Industries; Ltd.
发明人:
申请号:
EP14754619.6
公开号:
EP2959912A1
申请日:
2014.02.20
申请国别(地区):
EP
年份:
2015
代理人:
摘要:
The present invention aims to provide a wound healing agent that inhibits bacterial growth, promotes granulation tissue formation and epithelization, and minimizes foreign body reaction in the granulation tissue. The wound healing agent of the present invention contains protein (A) and water, wherein the protein (A) contains: GAGAGS (1); and an amino acid sequence (X) and/or an amino acid sequence (X'), and the total percentage of β turns and random coils in the protein (A) as determined by circular dichroism spectroscopy is 60 to 85%, and the percentage of the total number of amino acid residues in the amino acid sequences (X) and (X') is 50 to 70% of the total number of amino acid residues in the protein (A). Amino acid sequence (X): at least one amino acid sequence selected from the group consisting of VPGVG (2), GVGVP (3), and GAHGPAGPK (4). Amino acid sequence (X'): an amino acid sequence in which 1 or 2 amino acid residues in the amino acid sequence (X) are independently replaced by a lysine (K) or arginine (R) residue.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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