A photon-counting system includes photon-counting detectors that output photon-counting signals to indicate a number of photons impinging on the photon-counting detectors. The system also includes analog-to-digital conversion circuits, which convert one of the photon-counting signals into a digital photon-counting signals, and a processor that processes the digital photon-counting signals to extract information from the photon-counting signals. The information extracted can include a photon-counting rate. An intelligent multiplexer that, based on the photon-counting rate, modifies interconnection of the photon-counting detectors and analog-to-digital conversion circuits and provides digital photon-counting signals for a selected set of the analog-to-digital converters to the processor.
