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PEPTIDE MACROCYCLES AND USE THEREOF IN THE TREATMENT OF BACTERIAL INFECTIONS
专利权人:
Hoffmann-La Roche Inc.
发明人:
Konrad BLEICHER,Jérôme HERT,Carsten KROLL,Fabian DEY
申请号:
US16596243
公开号:
US20200040032A1
申请日:
2019.10.08
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The present invention provides compounds of formula (I)wherein R1, R2, R3, R4, R5, R6, R7, R8, R8′;, R9, R9′;, X1, X2, X3, X4, X5, X6, X7, X8, X9 and X10 are as described herein, as well as pharmaceutically acceptable salts thereof. Further the present invention is concerned with the manufacture of the compounds of formula (I), pharmaceutical compositions comprising them and their use as medicaments for the treatment of diseases and infections caused by Acinetobacter baurnannii.
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