MACROCYCLES PEPTIDIQUES ET LEUR UTILISATION DANS LE TRAITEMENT DES INFECTIONS BACTÉRIENNES

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专利权人:

F. Hoffmann-La Roche AG

发明人:

申请号：

EP17165654.9

公开号：

EP3388445A1

申请日:

2017.04.10

申请国别(地区):

EP

年份:

2018

代理人:

摘要：

The present invention provides compounds of formula (I)wherein R1, R2, R3, R4, R5, R6, R7, R8, R8', R9, R9', X1, X2, X3, X4, X5, X6, X7, X8, X9 and X10 are as described herein, as well as pharmaceutically acceptable salts thereof. Further the present invention is concerned with the manufacture of the compounds of formula (I), pharmaceutical compositions comprising them and their use as medicaments for the treatment of diseases and infections caused by Acinetobacter baumannii.

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