To provide a culture method for growing corneal endothelial cells while maintaining normal function.SOLUTION: Provided is a culture normalizing agent for corneal endothelial cells, comprising a fibrogenesis inhibitor, specifically, a transforming growth factor (TGF) β signal inhibitor. Provided is a medium for normal culture of corneal endothelial cells, comprising the culture normalizing agent and a culture component of corneal endothelium. Provided is a method for normally culturing corneal endothelial cells, comprising culturing corneal endothelial cells using the culture normalizing agent or the medium.SELECTED DRAWING: None【課題】角膜内皮細胞を、正常な機能を保ったまま増殖させる培養方法の提供。【解決手段】線維化抑制剤、詳細には、トランスフォーミング増殖因子（ＴＧＦ）βシグナル阻害剤を含む角膜内皮細胞の培養正常化剤。培養正常化剤と角膜内皮の培養成分とを含む、角膜内皮細胞を正常に培養するための培地。培養正常化剤、又は培地を用いて角膜内皮細胞を培養する工程を包含する、角膜内皮細胞を正常に培養する方法。【選択図】なし
