Disclosed is a process for preparing a drug-containing polymeric micelle composition. The process includes: dissolving a drug and an amphiphilic block copolymer into an organic solvent； and adding water or an aqueous solution to the resultant mixture in the organic solvent to form polymeric micelles, wherein the process requires no special operation to remove the organic solvent prior to the addition of water or aqueous solution. The process is simple, reduces the processing time, and is amenable to large-scale production.
