To provide novel external or internal preparations that are excellent in hyaluronic acid production promoting action, collagen production promoting action, and MMP inhibitory effect.SOLUTION: The extract of Ecklonia kurome and Sargassum fulvellum have excellent hyaluronic acid production promoting action, collagen production promoting action, and MMP inhibitory effect, as well as also have excellent stability. The extract of Ecklonia kurome and Sargassum fulvellum can be used not only in the esthetic field such as skin aging prevention, but in the medical field such as the suppression of functional deterioration due to aging, cancer prevention and treatment, and can be expected to be applied to foods, cosmetics, quasi-drugs and pharmaceuticals.SELECTED DRAWING: None【課題】ヒアルロン酸産生促進作用、コラーゲン産生促進作用及びＭＭＰ阻害効果に優れた新規な外用剤又は内用剤を提供する。【解決手段】クロメ及びホンダワラの抽出物は、優れたヒアルロン酸産生促進作用、コラーゲン産生促進作用及びＭＭＰ阻害効果を有し、安定性にも優れていた。クロメ及びホンダワラの抽出物は、皮膚の老化予防といった美容分野だけでなく、老化による機能低下の抑制、ガンの予防、治療等といった医療分野にも利用でき、食品、化粧品、医薬部外品及び医薬品等への応用が期待される。【選択図】なし
