Pharmaceutical composition comprising an Antibody that specifically recognizes and ciclofosfamida.1. cds8- a Pharmaceutical Combination comprising an Antibody that specifically recognizes at least CD38 and Cyclophosphamide, in which the Antibody is capable of destroying a CD38 + cells by apoptosis, Antibody dependent Cellular cytotoxicity (ADCC) and compleme dependent cytotoxicity NTO (CDC) 2.- The combination according to claim 1, in which the Antibody is an Antibody humanizado.3.- The combination according to claim 2, in which the Antibody comprising one or more of the complementarity determining regions that have a sequence of amino acids selected from the group consisting of the SEQ ID: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35 and 36.4.- The combination according to claim 3, which comprises at least one such Antibody heavy chain and at least a light chain, in which the heavy chain has an Amino Acid Sequence represented by SEQ ID no: 66And the heavy chain complementarity determining regions includes three Sequential with the Amino Acid Sequence represented by the SEQ ID Nos: 13, 14 and 15, and in which the light chain has an Amino Acid Sequence selected from the group of SEQ ID Nos: 62 And 64And in this light chain complementarity determining regions includes three Sequential with the Amino Acid Sequence represented by the SEQ ID Nos: 16, 17 and 18.Composición farmacéutica que comprende un anticuerpo que reconoce específicamente CDS8 y ciclofosfamida.1.- Una combinación farmacéutica que comprende un anticuerpo que reconoce específicamente CD38 y al menos ciclofosfamida, en la que dicho anticuerpo es capaz de destruir una célula CD38+ por apoptosis, citotoxicidad celular dependiente de anticuerpos (ADCC) y citotoxicidad dependiente de complemento (CDC).2.- La combinación según la reivindicación 1, en la que dicho anticuerpo es un anticuerpo humanizado.3.- La combinación según l
