The present invention relates to peptides, nucleic acids and cells for use inimmunotherapeuticmethods. In particular, the present invention relates to the immunotherapy ofcancer. The presentinvention furthermore relates to tumor-associated cytotoxic T cell (CTL)peptideepitopes, alone or in combination with other tumor-associated peptides thatserve as activepharmaceutical ingredients of vaccine compositions that stimulate anti-tumorimmune responses.The present invention relates to more than 70 novel peptide sequences andtheir variantsderived from HLA class I and HLA class II molecules of human tumor cells thatcan beused in vaccine compositions for eliciting anti-tumor immune responses.