Niigata University;Stelic Institute Of Regenerative Medicine, Stelic Institute & Co.
发明人:
申请号：
EP17180709.2
公开号：
EP3284486A1
申请日:
2008.06.27
申请国别(地区):
EP
年份:
2018
代理人:
摘要：
It is intended to provide a method which comprises administering a physiologically active substance to a target submucosal tissue and thus fixing and expressing the physiologically active substance specifically to the tissue. It has been found out that when a physiologically active substance is directly administered to a submucosal tissue without using a carrier, the physiologically active substance is safely and effectively fixed to the administration site over a long time without disappearing or diffusing and, moreover, plays a reservoir-like role to thereby exert its effect. It has been also found out that the physiologically active substance having been administered in the above-described manner would not affect organs other than the organ to which it is to be administered, thereby exerting a therapeutic effect.
