PURPOSE: A composition containing diosgenin or pharmaceutically acceptable salt thereof is provided to promote proliferation, differentiation, and mineralization of osteoblast. CONSTITUTION: A composition for promoting osteoblast contains diosgenin or pharmaceutically acceptable salt thereof. Diosgenin is isolated from yam. The concentration of the diosgenin is 1-3 uM. A composition for preventing or treating bone metabolism contains diosgenin or pharmaceutically acceptable salt thereof. The bone metabolism is osteoporosis, bone metastatic lesion, rheumatic or degenerative arthritis, periodontal diseases, inflammatory bone absorption or Paget's disease. A food composition for improving bone function contains diogenin or pharmaceutically acceptable salt.본 발명은 디오스게닌(diosgenin) 또는 약학적으로 허용되는 염을 포함하는 조골세포 분화 촉진용 및 칼슘화 촉진용 조성물에 관한 것이다. 또한 본 발명은 디오스게닌(diosgenin) 또는 약학적으로 허용되는 염을 포함하는 골대사 질환 예방 또는 치료용 조성물 및 골 기능 개선 식품용 조성물에 관한 것이다.
