YAMAMOTO KENTA,KISHIDA TSUNAO,YAMAMOTO TOSHIRO,MAZDA OSAM
申请号:
IN201617002925
公开号:
IN201617002925A
申请日:
2016.01.27
申请国别(地区):
IN
年份:
2016
代理人:
摘要:
The present invention relates to: a method for preparing an osteoblast from a somatic cell by introducing a bone related gene or an expression product thereof and a reprogramming related gene or an expression product thereof to a somatic cell of a mammal or introducing a reprogramming related gene or an expression product thereof independently to a somatic cell of a mammal the method for preparing an osteoblast in which the bone related gene is at least one gene selected from the group consisting of Runx2 (R) Osterix (O) and Dlx5 (D) and the reprogramming related gene is at least one gene selected from the group consisting of the Oct family c Myc (M) L Myc (L) the Klf family Lin 28 and Sox2; and an osteoblast prepared by the abovementioned method.