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Solid forms of a thiophosphoramidate nucleotide prodrug
专利权人:
ALIOS BIOPHARMA INC.
发明人:
KULDIPKUMAR ANUJ K.,JUNG YOUNG CHUN,MEDEK ALES,FERRIS LORI ANN,MUDUNURI PRAVEEN,WILLCOX DAVID RICHARD,WALDO MICHAEL,NUGENT WILLIAM ALOYSIUS
申请号:
NZ63160113
公开号:
NZ631601A
申请日:
2013.03.11
申请国别(地区):
NZ
年份:
2016
代理人:
摘要:
The present application relates to solid state forms, for example, crystalline forms of 2&rsquo-C-methyluridine-5&rsquo-(O-phenyl-N-(S)-1-(isopropoxycarbonyl)ethyl)thiophosphoramidate (Compound 1), pharmaceutical compositions that can include one or more solid forms of 2&rsquo-C-methyluridine-5&rsquo-(O-phenyl-N-(S)-1-(isopropoxycarbonyl)ethyl)thiophosphoramidate, and methods of treating or ameliorating diseases and/or conditions with one or more solid forms of 2&rsquo-C-methyluridine-5&rsquo-(O-phenyl-N-(S)-1-(isopropoxy carbonyl)ethyl)thiophosphoramidate. Also disclosed herein are methods of treating diseases and/or conditions with one or more solid forms of 2&rsquo-C-methyluridine-5&rsquo-(O-phenyl-N-(S)-1-(isopropoxycarbonyl)ethyl)thiophosphoramidate in combination with one or more other agents.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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