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SOLID FORMS OF A THIOPHOSPHORAMIDATE NUCLEOTIDE PRODRUG
专利权人:
发明人:
Anuj K Kuldipkumar,Ales Medek,Lori Ann Ferris,Praveen Mudunuri,Young Chun Jung,David Richard Willcox,Michael Waldo,William Aloysius Nugent
申请号:
US15210509
公开号:
US20160318969A1
申请日:
2016.07.14
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The present application relates to solid state forms, for example, crystalline forms of 2′-C-methyluridine-5′-(O-phenyl-N—(S)-1-(isopropoxycarbonyl)ethyl)thiophosphoramidate, pharmaceutical compositions that can include one or more solid forms of 2′-C-methyluridine-5′-(O-phenyl-N—(S)-1-(isopropoxycarbonyl)ethyl)thiophosphoramidate, and methods of treating or ameliorating diseases and/or conditions with one or more solid forms of 2′-C-methyluridine-5′-(O-phenyl-N—(S)-1-(isopropoxycarbonyl)ethyl)thiophosphoramidate. Also disclosed herein are methods of treating diseases and/or conditions with one or more solid forms of 2′-C-methyluridine-5′-(O-phenyl-N—(S)-1-(isopropoxycarbonyl)ethyl)thiophosphoramidate in combination with one or more other agents.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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