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ANTI-TGF-BETA ANTIBODIES AND THEIR USE
专利权人:
SANOFI
发明人:
KODURI, Rao,FINN, Patrick,LIU, Feng,MALKOVA, Natalia,QIU, Huawei,THEILHABER, Joachim,BROWEN, Kevin,WINTER, Christopher,GREGORY, Richard, C.,MANKOO, Parminder,POLLARD, Jack, R.,SHAPIRO, Gary,YU,
申请号:
CR20190375
公开号:
CR20190375A
申请日:
2018.01.19
申请国别(地区):
CR
年份:
2019
代理人:
摘要:
The invention provides a better pan TF Di antibody for the treatment of TGF Di transmitted diseases,Including autoimmune diseases, fiber diseases and cancer The invention provides an improved pan TGF - for treatment of conditions that are mediated by TGF -,including autoimmune diseases, fibrotic conditions, and cancers. Also provided are methods and uses of the antibody in conjunction with other immunomodulatory agents such as an anti-PD-1 antibody.La invención proporciona un anticuerpo pan-TGF-ß mejorado para el tratamiento de afecciones que están mediadas por TGF-ß, incluyendo enfermedades autoinmunitarias, afecciones fibróticas, y cánceres. También se proporcionan usos y usos del anticuerpo junto con otros agentes inmunomoduladores tales como un anticuerpo anti-PD-1.The invention provides an improved pan-TGF-ß antibody for treatment of conditions that are mediated by TGF-ß, including autoimmune diseases, fibrotic conditions, and cancers. Also provided are methods and uses of the antibody in conjunction with other immunomodulatory agents such as an anti-PD-1 antibody.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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