A compound having the following formula (II) or a pharmacologically acceptable salt thereof is used as a P2X4 receptor antagonist:wherein each of R11 and R12 is hydrogen, C1-8 alkyl or the likeR13 is hydrogen, C1-8 alkyl or the likeR14 is hydrogen, C1-8 alkyl, C1-8 alkoxy, C1-8 alkyl having 1-3 halogens, C1-8 hydroxyalkyl, halogen, hydroxyl, nitro, cyano, amino, C1-8 alkylamino, benzenesulfonylamino optionally having a substituent, a heterocyclic group optionally having a substituent or the like andthe condensed ring consisting of W1 and the neighboring benzene ring is naphthalene, tetrahydronaphthalene, or indan ring.
