A compound having the following formula (II) or a pharmacologically acceptable salt thereof is used as a P2X4 receptor antagonist:wherein each of R11 and R12 is hydrogen, C1-8 alkyl or the likeR13 is hydrogen, C1-8 alkyl or the likeR14 is C1-8 alkoxy, hydroxyl, cyano, a heterocyclic group optionally having a substituent or the like andthe condensed ring consisting of W1 and the neighboring benzene ring is naphthalene ring or the like.
