There is provided herein in novel hyaluronic acid-base materials in-situ gelling wound and other environment, which these Biocompatibilities have good Kinetics of gelation with. The hydrogel of generation has ideal rheological property. The present invention includes novel agent, to form crosslinked hyaluronic acid hydrogel, for medical application and has desired tunable physical property with good dynamics. Method disclosed herein is given in text uses new material wound care and other medical environments.
