The present invention provides a bilirubin reducing means which can minimize a risk such as the onset of an infection or the occurrence of blood coagulation and can reduce physical, temporal and economical burdens imposed on a patient suffering from liver dysfunction. A bilirubin denaturating apparatus includes a dialyzing portion which has a dialyzing column for performing dialysis of blood using hollow fibers incorporated therein an infusion supply portion which supplies an infusion used for dialysis in the dialyzing portion to the dialyzing portion and a blood circulating portion which feeds blood to the dialyzing portion and returns the blood dialyzed by the dialyzing portion, wherein the dialyzing portion includes a radiation means which radiates green light to the hollow fibers, and the radiation means radiates the green light to the hollow fibers for converting fat-soluble bilirubin in the blood flowing in the inside of the hollow fibers into water-soluble bilirubin thus eluting the water-soluble bilirubin in the infusion.
