DERIVES D'ACIDE 2-UREIDO-6-HETEROARYL-3H-BENZOIMIDAZOLE-4-CARBOXYLIQUE ET COMPOSES ASSOCIES UTILISES COMME INHIBITEURS DE LA GYRASE ET/OU DE LA TOPOISOMERASE IV AUX FINS DE TRAITEMENT D'INFECTIONS BACTERIENNES
CHARIFSON, PAUL,DEININGER, DAVID D.,DRUMM, JOSEPH,GRILLOT, ANNE-LAURE,LIAO, YUSHENG,OLIVER-SHAFFER, PATRICIA,STAMOS, DEAN
申请号:
CA2489128
公开号:
CA2489128C
申请日:
2003.06.11
申请国别(地区):
CA
年份:
2012
代理人:
摘要:
The present invention relates to compounds of formula I, wherein X, Q, W, R1,R2 and R3 are as defined in the claims, which inhibit bacterial gyrase and/orTopo IV and pharmaceutically acceptable compositions comprising saidcompounds. These compounds, and compositions thereof, are useful in treatingbacterial infection. Accordingly, the present invention also relates tomethods for treating bacterial infections in, mammals. The present inventionalso relates to a method for preparing these compounds.