Jane Rapsey;Martin Svehla;Christopher Miller;Peter Schuller;Cochlear Limited
发明人:
Rapsey, Jane,Svehla, Martin,Schuller, Peter,Miller, Christopher Robert
申请号：
AU2013202771
公开号：
AU2013202771A1
申请日:
2013.01.18
申请国别(地区):
AU
年份:
2013
代理人:
摘要：
#$%^&*AU2013202771A120130815.pdf#####Atty. Docket No. 62367-819489 Client Ref. No. CID1786USCO1 ABSTRACT Implantable drug-doped component, e.g., a cochlear implant, including host material, a hostembedded drug, a sacrificial material integrated with the host. Sacrificial material facilitates release of drug from the component. Sacrificial material facilitates release through creation of voids in the host upon dissolution of sacrificial material upon contact with a solvent, e.g., perilymph fluid upon implant. Host can be polysiloxane, or silicone rubber. Drug can be antiinflammatory, growth factor, antibody, anti-oxidant, antibiotic, corticosteroid. Sacrificial material can be: glucose monomer, sugar, cyclodextrin, dissolvable or resorbable at implant site, a salt, bioresorbable material, hyaluronic acid, polyurethane, polyester, polyamide, polyvinyl alcohol, polyacrylic acid. Sacrificial material can be the host, and can facilitate release of drug through changing a property of sacrificial material, e.g., by exposing component to ethanol wash. For a cochlear implant, drug doped material can be applied to a non-stimulating surface of the electrode array, and can be a physical feature of stimulating medical device, e.g., soft tip, ridge, spine. For a cochlear implant the drug-doped material can excluded from the basal side of the most basal electrode contact. Page 17 US2008 3184569.1
