ДЕЙВИС Джеймс В. (US),КИТЕЛСОН Говард Аллен (US),МИДОУЗ Дэвид Л. (US)
申请号：
RU2012103982/15
公开号：
RU2012103982A
申请日:
2010.07.07
申请国别(地区):
RU
年份:
2013
代理人:
摘要：
1. A sterile aqueous ophthalmic composition containing ethylene oxide-butylene oxide (EO-BO) block copolymer with the formula (EO) (BO) and galactomannan. 2. The composition according to claim 1, where m has an average value of 45 and n has an average value of from 9 to 18.3. The composition according to claim 1, where m has an average value of 45 and n has an average value of from 9 to 11.4. The composition of claim 1, wherein said galactomannan is guar or a derivative thereof. The composition of claim 4, wherein said guar or guar derivative is selected from the group consisting of: native guar, hydroxypropyl guar and galactomannan hydroxypropyl guar. The composition according to claim 1, wherein said EO-BO block copolymer is present in a concentration of from 0.001 to 1.0% w / v. The composition according to claim 1, where the specified EO-IN block copolymer is present in a concentration of from 0.01 to 0.1% wt./about. 8. The composition of claim 1, wherein said galactomannan is present in a concentration of from 0.01 to 2.0% w / v. The composition of claim 1, wherein said galactomannan is present in a concentration of 0.05 to 0.25% w / v. A method for treating dry eyes, comprising topical administration of an ophthalmic composition, wherein said composition comprises an ethylene oxide-butylene oxide (EO-BO) block copolymer with the formula (EO) (BO) and galactomannan. 11. The method according to claim 10, where m has an average value of 45, and n has an average value from 9 to 18.12. The method according to claim 10, where m has an average value of 45, and n has an average value of from 9 to 11.13. The method of claim 10, wherein said galactomannan is guar or a derivative thereof. The method of claim 13, wherein said guar or guar derivative is selected from the group consisting of: native guar, hydroxypropyl guar and hydroxypropyl guar galactomannan. The method of claim 10, wherein said EO-BO��1. Стерильная водная офтальмологическая композиция, содержащая этилено
