Daniel Rees Allen,George Martin Buckley,Roland Bürli,John Richard Davenport,Natasha Kinsella,Christopher James Lock,Christopher Lowe,Stephen Robert Mack,William Ross Pitt,Andrew James Ratcliffe,Marian
申请号:
US12809394
公开号:
US08399483B2
申请日:
2008.12.17
申请国别(地区):
US
年份:
2013
代理人:
摘要:
A series of heteroaryl-substituted quinoxaline and quinoline derivatives, being selective inhibitors of PI3 kinase enzymes, are accordingly of benefit in medicine, for example in the treatment of inflammatory, autoimmune, cardiovascular, neurodegenerative, metabolic, oncological, nociceptive or ophthalmic conditions, said substituted derivatives having the general formula