Roland Bürli;Andrew Pate Owens;Gilles Raphy;Alan Findlay Haughan;Mizio Matteucci;Andrew Sharpe
发明人:
Roland Bürli,Alan Findlay Haughan,Mizio Matteucci,Andrew Pate Owens,Gilles Raphy,Andrew Sharpe
申请号:
US13508962
公开号:
US08637543B2
申请日:
2010.11.11
申请国别(地区):
US
年份:
2014
代理人:
摘要:
A series of quinoline and quinoxaline derivatives, substituted by a fused bicyclic pyridine or pyrimidine moiety attached via an alkylene chain optionally linked to a heteroatom, being selective inhibitors of P13 kinase enzymes, are accordingly of benefit in medicine, for example in the treatment of inflammatory, autoimmune, cardiovascular, neurodegenerative, metabolic, oncological, nociceptive or ophthalmic conditions.