HAKOZAKI, TOMOHIRO,LAUGHLIN, LEO TIMOTHY, II,SABINO, MICHAEL CHRISTOPHER
申请号:
CA2926217
公开号:
CA2926217C
申请日:
2014.10.23
申请国别(地区):
CA
年份:
2018
代理人:
摘要:
A cosmetic composition for topical application to skin is provided. The cosmetic composition includes vitamin B3 compound, a ricinoleate compound and a dermatologically acceptable carrier. The vitamin B3 compound and the ricinoleate beneficially or even synergistically up-regulate proteasomal protease activity as evidenced by a higher observed net luminescence value relative to the calculated net luminescence value in B16 melanoma cells.