Tomohiro Hakozaki,Leo Timothy Laughlin, II,Michael Christopher Sabino
申请号：
US14521742
公开号：
US09597271B2
申请日:
2014.10.23
申请国别(地区):
US
年份:
2017
代理人:
摘要：
A cosmetic composition for topical application to skin is provided. The cosmetic composition includes vitamin B3 compound, a ricinoleate compound and a dermatologically acceptable carrier. The vitamin B3 compound and the ricinoleate beneficially or even synergistically up-regulate proteasomal protease activity as evidenced by a higher observed net luminescence value relative to the calculated net luminescence value in B16 melanoma cells.
