The Trustees of the University of Pennsylvania;Advaxis, Inc.
发明人:
申请号：
EP14195065.9
公开号：
EP2859899A1
申请日:
2008.05.12
申请国别(地区):
EP
年份:
2015
代理人:
摘要：
A recombinant Listeria strain expressing a kallikrein-related peptidase 3 (KLK3) peptide, wherein the sequence of the KLK3 peptide comprises a sequence selected from SEQ ID NOs: 27, 29-32, 34, and 36-39, or a sequence greater than 95% identical thereto, wherein the KLK3 peptide is in the form of a fusion peptide and further comprises a non-KLK3 peptide, wherein the non-KLK3 peptide is an ActA peptide or a PEST sequence, and wherein the non-KLK3 enhances the immunogenicity of the fusion peptide.
